Please note this link is one-time use only and is valid for only 24 hours. About. The program with Bristol Myers Squibb is targeting STAT3. We'll e-mail you a link to set a new password. Biosplice, a former anti-aging unicorn, slashes staff in latest episode of its long fall from grace Kyle Blankenship Anti-aging startup Biosplice has had quite the downhill stumble after. Founded in 1993 by brothers Tom and David Gardner, The Motley Fool helps millions of people attain financial freedom through our website, podcasts, books, newspaper column, radio show, and premium investing services. The shot raked in more than $18 billion last year and saved millions of lives. Funds from the IPO and the Series B will support development of the companys oncology pipeline. Chief Operating Officer. Learn more about Biosplice Therapeutics stock. SAN DIEGO, Jan. 27, 2022 /PRNewswire/ -- Biosplice Therapeutics, Inc., a clinical-stage biotechnology company pioneering therapeutics based on CLK/DYRK kinase modulation for major diseases, . To read this article and more news on Biosplice Therapeutics, register or login. It's already testing its drug called CAN-2409 in prostate cancer, and then it's planning phase 3 for brain cancer next year. SAN DIEGO, June 21, 2021 (GLOBE NEWSWIRE) -- Biosplice Therapeutics, Inc. ("Biosplice"), a clinical-stage biotechnology company pioneering therapeutics based on alternative pre-mRNA splicing . Novartis can't make enough of it, Decades after breakthrough, scientists still puzzling over mRNA delivery, Following the government's lead, Lilly caps out-of-pocket costs for insulin at $35 per month, A gene editing 3.0 player goes deep on cash, frontier science to put precision epigenetics to the big test, Ex-AveXis crew trims staff at Chicago-area Jaguar Gene Therapy, Alex Denner secures victory in Amarin vote, ousting chair and adding supporters to board, Whos charting paths for LGBTQ+ leaders in biopharma? The company is headquartered in San Diego, California. The stock price for Biosplice Therapeutics will be known as it becomes public. Brian Orelli: IPOs lately have been really early-stage. The company asserts that medicines that can harness this process will help cure musculoskeletal, ummune and oncological disorders. With their platform's origins in small molecule-based Wnt pathway modulation, they develop therapeutics to address a range of degenerative diseases, regenerative medicine, and oncology. The German tech investor Kizoo Ventures is committing 300m of its own cash to biotech start-ups working on rejuvenation and healthy lifespan expansion. The company is also on the preclinical stages of developing an anti-Alzheimer's disease drug. The name Biosplice echoes our science much more than Samumed does.. At least those big pharma partners have looked at the early-stage preclinical data. Eli Lilly is looking to get ahead of any more federal action on insulin prices, announcing today that it will not only slash its most commonly used insulin by 70%, but cap out-of-pocket costs for those on commercial insurance at $35 per month just as the federal government recently did for those insured by Medicare. Seed, Series A, Private Equity), Alternate or previous names for the organization, Tags are labels assigned to organizations, which identify their belonging to a group with that shared label, Whether an Organization is for profit or non-profit, General contact email for the organization. If you're already an Endpoints subscriber, enter your email below for a If you own Biosplice Therapeutics pre-IPO shares and are considering selling, you can find what your shares could be worth on Forges secondary marketplace. That's right -- they think these 10 stocks are even better buys. The greatest drivers of growth in the global OA market include the launch of eight new pipeline therapies during the forecast period and a steadily climbing diagnosed prevalence in many . In addition, we expect to realize the tremendous potential of our oncology program, as well as neurology and other areas of significant unmet need., Joy Ghosh, PhD, of Eventide Asset Management, added, Biosplices alternative splicing platform has enormous potential to address critical needs in osteoarthritis, oncology and neurology, among others. Biosplice's mission is to restore health by delivering first-in-class therapies that harness alternative splicing. Just weeks after activist investor Alex Denner called for Amarins chairman to step down, the Irish biotechs shareholders have voted in Denners favor. They have two partners at Bristol Myers Squibb (BMY 0.83%) and Roche [Holding] (RHHBY 0.22%). Please note the magic link is "Mr. Johnson's vast experience ushering drugs from . Keith Speights owns shares of Bristol Myers Squibb. Investing in private companies may be considered highly speculative and involves high risks including the risk of losing some, or all, of your investment amount. Focused on tissue-level regeneration to treat aging related diseases, Biosplice states its mission is to "restore human health via novel therapies that use alternative splicing Both Moffitt Cancer Center and Mayo Clinic in Florida, not too far from Domingos and his family, said he would have to wait between three and a half and four months to get the treatment. All trademarks, logos and company names are the property of their respective owners. The data in the chart above is based on data derived from our proprietary XP calculation model and may be changed, adjusted and updated without prior notice. Now, the biotech is laying off a large swath of its staff as it undergoes a pipeline overhaul. Biosplice Therapeutics is developing first-in-class, small-molecule therapeutics based on pioneering science of alternative pre . Based in San Diego, CA, Biosplice is developing small-molecule therapeutics based on pioneering science of alternative pre-mRNA splicing. David Ricks, Eli Lilly CEO (David Paul Morris/Bloomberg via Getty Images), Catherine Stehman-Breen, Chroma Medicine CEO, Alex Denner (Mark Neuling/CNBC/NBCU Photo Bank via Getty Images), Hemolytic Anemia Sales Specialist, Rare Genetic Diseases, Biosplice, a former anti-aging unicorn, slashes staff in latest episode of its long fall from grace, Digital therapeutics: The key to maximizing the potential of medicinal assets, A radioactive prostate cancer therapy is a last lifeline for patients. Samumed made quite the entrance back in 2016, when it launched with some anti-aging programs and a whopping $12 billion valuation. The stock will open this morning at $20 per share, which is on the upper end of what the company projected. Jan 3, 2023 06:30am. They also plan to go public with an IPO this year. Internal digital and data science expertise is critical to developing a united value proposition that aligns the benefits of the digital and medicinal product. Funding Rounds Number of Funding Rounds 5 SaaS, Android, Cloud Computing, Medical Device), Where the organization is headquartered (e.g. This morning, two of those companies, Ikena Oncology andDesign Therapeutics, join Edgewise Therapeutics by trading on the exchange. Chief Financial Officer and Chief Business Officer of Biosplice Therapeutics, Inc. San Diego County, California, United States. Learn more at https://www.biosplice.com, Corporate Contact:Erich HorsleyBiosplice Therapeutics, [email protected], GLOBAL MARKETS-US stocks muted, Treasuries dip as inflation worries linger, Stock market news today: Stocks waver after key manufacturing data, Salesforce set to report earnings Thursday, Goldman Sachs tries to reset firm culture after three 'unusual' years, Shipping companies reach $97M California oil spill agreement. Gerostate Alpha raising $500k through WeFunder (Live Now). Equity securities are offered through EquityZen Securities. Tom Jones take zinc after sex or personal release. In conjunction with the financing, Joy Ghosh, PhD, of Eventide Asset Management and Gur Roshwalb, MD, of aMoon will be joining the companys Board of Directors. Other disorders the company will target with its GeneTac platform will include myotonic dystrophy type-1, and other indications that have yet to be publicly announced. Bioscience & Technology Business CenterThe University of KansasLawrence, Kansas. Biosplice Therapeutics's latest funding round was a Series B for $120M on April 15, 2021. Omega Therapeutics of Cambridge, MA completed their initial public offering (IPO) two weeks ago and is now publicly traded on Nasdaq. When he told a group of senior scientists about his ideas for drug delivery at a Chinese restaurant in 1979, one of them blew cigar smoke in his face. It might be worth that much, but on a risk-adjusted basis, I just don't know. AT-GAA consists of biologic cipaglucosidase alfaand miglustat, a stabilizer of the biologic. Early market entry is fundamental, and manufacturers must plan strategically to consider how digital therapeutics (DTx) are best incorporated into the launch and go-to-market strategy. To make the world smarter, happier, and richer. Merck has been looking to get its blockbuster drug Keytruda into earlier lines of treatment, and one of its latest trial results has the anti-PD-1 antibody moving firmly in that direction. Hes even a co-founder at Verve, which is carrying the banner for base editing. Biosplice Therapeutics is in the medical research and development for tissue-level regeneration. Funds from that round, as well as the IPO, will be used to advance the companys muscular dystrophy program, as well as other indications. Biosplice Therapeutics is a private company and not publicly traded. *** - To view the data, please log into your account or create a new one. The malignant cells permeated his bones, kidney, lungs and liver, and in December, his oncologist told him there was no point in continuing chemotherapy treatment. Finances from the IPO, as well as the cash from the Series B, will be used to develop treatments for nucleotide repeat expansion disorders, including its lead program in Friedreich ataxia, which is expected to enter clinical development in the first half of 2022. Its scientific platform is based on biological discoveries that govern tissue specialization and enable it to selectively eliminate harmful proteins using small molecules. | Source: Get stock recommendations, portfolio guidance, and more from The Motley Fool's premium services. Log in. Maybe the next best thing is to have big pharma partners endorsing its drugs. Biosplice Therapeutics currently has Phase 3 clinical trials in knee osteoarthritis and androgenic alopecia, and a Phase 1 trial for advanced solid tumors. Below are the key stats of Biosplice Therapeutics patent prosecution at the USPTO. Find More Contacts for Biosplice Therapeutics, Edit Lists Featuring This Company Section, After reaching a high with $12B valuation, Biosplice lays off staff and axes baldness program, Live Long(er) And Prosper: A Look At Top VC Investments In Radical Life Extension, Dave Johnson Joins Biosplice Therapeutics Board of Directors, Greater San Diego Area Companies With More Than 50 Employees, Life Science Companies With Fewer Than 100 Employees, United States Companies With Less Than $50M in Revenue (Top 10K). Biosplice Therapeutics is an American pharmaceutical company engaged in the development of alternative splicing technologies. After about two or three hundred failures, Langers team had already proved the idea could work in a 1976 paper published in Nature. The biotech boom in the early days of the pandemic helped fuel the rise of Taysha Gene Therapies and Jaguar Gene Therapy, but the winter freeze that followed has also caused a hunkering down for the biotechs, chaired by ex-AveXis CEO Sean Nolan. When developed in combination with a medicinal asset, digital therapeutics enable significant market differentiation and significant benefits for stakeholdersfrom optimizing patient outcomes to supporting more efficient generation of compelling real-world data Feb 2019 - Jan 20212 years. San Diego, California. Active, Closed, Last funding round type (e.g. EDG-5506 is currently being assessed in a Phase I study.

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